A distinct signaling pathway called TNF- drives the transformation of epithelial cells into aggressive tumor cells. During cancer progression, cells activate their own TNF- program and become invasive ...

HOXB13, a B-class homeobox transcription factor, sits at the hub of developmental gene networks yet has emerged as a double-edged sword in human cancer. While indispensable for embryonic patterning ...

Even before a tumor in the pancreas becomes discernible, an activated cancer gene actively remodels its future environment ...

Notoriously tricky to detect, pancreatic cancer also often resists traditional therapy. So, researchers are urgently looking for new ways to disrupt tumor formation. Though scientists know that the ...

The same cellular renewal that keeps our bodies healthy might also fuel the growth of cancer. A UC Merced biologist has found that the brain could hold the key to stopping it. Professor Néstor Oviedo, ...

A new study suggests that chronic stress and an unhealthy diet may work together to fuel the early development of pancreatic cancer, shedding light on how lifestyle factors contribute to one of the ...