Here, we describe a patient with an early onset of endocapillary glomerulonephritis and CFH deficiency. Genetic analyses revealed uniparental isodisomy and a novel mutation as the unusual molecular ...
A recent article posted to the medRxiv* preprint server discussed the role of complement factor H-related protein 5 (CFHR5) in venous thromboembolism (VTE) patients and hospitalized coronavirus ...
Changes in PD-L1 and tumor mutational burden between paired samples and relationship to immune checkpoint inhibitor outcomes in non-small cell lung cancer. This is an ASCO Meeting Abstract from the ...
Among the most significant genetic risk factors for age-related macular degeneration is the Y402H variant of complement factor H, which, along with its splice isoform FHL-1, impairs binding to the ...
Factor H is a soluble complementary glycoprotein present in the blood plasma that serves the primary function of controlling the alternative pathway in blood and maintaining homeostasis. In vitro ...
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Gemini Therapeutics, a clinical stage precision medicine company developing innovative treatments for genetically defined age-related macular degeneration (AMD), ...
Eleva, a pioneer in discovering and developing previously inaccessible biologics based on a breakthrough technology platform, announced the first dosing in its phase 1 clinical study investigating the ...
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