A virus may be microscopic, but it contains thousands of nucleic acid bases strategically packaged into a protein shell. Knowing how the virus organizes these vast information stores in a compact ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

Researchers at the Pacific Northwest Research Institute (PNRI) and collaborating institutions have made a groundbreaking discovery that could significantly advance our understanding of genomic ...

DNA's iconic double helix does more than "just" store genetic information. Under certain conditions, it can temporarily fold ...

The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible to the cellular machinery that works to express the right genes at the ...

Scientists have discovered that DNA behaves in a surprising way when squeezed through tiny nanopores, overturning a long-held ...

DNA, the blueprint of life, is best known for its fundamental role as genetic material—storing and transmitting biological information through the precise sequence of its bases. For decades, this ...

Similarly to the artistic technique of folding paper into ornate shapes, DNA origami is a self-assembling technique of precisely folding single-stranded DNA scaffolds into well-defined nanostructures.