Explore the SHANK3 knockout model to enhance research in Phelan-McDermid syndrome and neurodevelopmental disorders.
Aconsortium of 17 laboratories worldwide has presented results contradicting a highly cited study that described a technique to create conditional knockout mice using CRISPR. The preprint, published ...
Species: Mouse Genes: Gba1 Modification: Gba1: Conditional Knock-out Disease Relevance: Parkinson's Disease Strain Name: B6.129-Gba1 tm1Clk /J Genetic Background: Backcrossed 11 generations to ...
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