In drug discovery and research projects, an important focus is the determination and characterization of binding interactions between proteins and low molecular weight (LMW) ligand interactions.

All biochemical reactions involve recognition, binding, and the formation of noncovalent complexes. Many small molecule drugs act by selectively binding to protein or nucleic acid targets and altering ...

In this on demand webinar we explain the basics of a widely used analytical technique. Titration is one of the most frequently used techniques in quantitative analysis, its use ranging across various ...

Isothermal titration calorimetry (ITC) can measure heat emission or absorption during binding interactions between proteins and low-molecular weight (LMW) ligands, a focus area of drug discovery and ...

ACCORDING to several authors 1,2, the direct titration of calcium and magnesium with ethylene-diamine tetraacetate has yielded very good results, especially in the determination of water hardness and ...