RNA (ribonucleic acid) editing is a post-transcriptional alteration of RNA sequences and structures via modification, deletion or insertion of nucleotides. This process has been detected in eukaryotes ...

'Prime editing' combines two key proteins and a new RNA to make targeted insertions, deletions, and all possible single-letter changes in the DNA of human cells A team from the Broad Institute of MIT ...

Researchers have developed a new tool -- dubbed SATI -- to edit the mouse genome, enabling the team to target a broad range of mutations and cell types. The new genome-editing technology could be ...

CRISPR-based genome engineering revolutionized the gene-editing field by making experimental workflows considerably easier, faster, and more efficient than previous methods. Still, generating reliable ...

One type of DNA has remained beyond the reach of precision genome editing techniques like CRISPR. Mitochondrial DNA has remained inaccessible to those methods because the guide RNA molecules used to ...