Chronic kidney disease (CKD) is a public health challenge that affects more than 800 million people worldwide. 1 CKD can be caused by a variety of disease processes. Many causes are difficult to ...

In the 1990s, Lee Sweeney, a physiologist at the University of Pennsylvania, demonstrated that inserting the gene encoding insulin-like growth factor 1 (IGF-1) into the muscle cells of mice increased ...

Most organisms on Earth have the same basic genetic code, but it comes with some flaws. Scientists sought to work out those errors by creating their own artificial genome, which replaced E. coli’s ...

Deep-learning model decodes the regulatory effects of DNA changes ...

Hunter syndrome, also called mucopolysaccharidosis II, is an X-linked genetic lysosomal disorder caused by loss-of-function mutations in the IDS gene, encoding iduronate-2-sulfatase (I2S). I2S is a ...

Researchers have discovered that mice possess a natural form of gene therapy, a non-coding RNA that can sidestep genetic mutations. They were able to engineer a programmable version that recognized ...

Could the library of the future replace bookshelves with petri dishes? New research into the possibility of storing information in DNA has already preserved words by Shakespeare and Martin Luther King ...

Here’s what you’ll learn when you read this story: Most organisms on Earth have the same basic genetic code, but it comes with some flaws. Scientists sought to work out those errors by creating their ...