Ahmar U. Zaidi, MD: As far as preventive therapies go, hydroxyurea is the mainstay of therapy in sickle cell disease. And hydroxyurea is quite an interesting drug that has been studied very ...

SAN DIEGO -- Treatment with hydroxyurea led to more hematologic dose-limiting toxicities (DLTs) compared with placebo in patients with hemoglobin SC, a milder form of sickle cell disease (SCD), a ...

Hydroxyurea remains effective over the long term among children with sickle cell disease, real-world data suggested. The average time on hydroxyurea was 5 years, with many children on the therapy for ...

New research shows hydroxyurea reshapes DNA replication in cancer cells, revealing stress responses that may help design ...

Children with sickle cell disease had improved lung function after treatment with hydroxyurea, according to a study presented at the American Thoracic Society (ATS) 2016 International Conference.

Please provide your email address to receive an email when new articles are posted on . Despite it being the standard of care for treating vasocclusive disease associated with sickle cell disease, ...

A 73-year-old man with a history of chronic myelogenous leukemia presented with multiple ulcers on both legs (Figure 1). The ulcers were extremely painful. The patient had no history of diabetes or ...

Hydroxyurea remains effective long-term in reducing emergency department visits and hospital days for children living with sickle cell disease (SCD), according to new research published in Blood ...

Please provide your email address to receive an email when new articles are posted on . Treatment with hydroxyurea reduced the incidence of acute and chronic complications, including painful crises, ...

Adding hydroxyurea to the selective inhibitor of Janus kinase 1 and 2 could elicit a high clinical response and increased ruxolitinib exposure for patients with hyperproliferative forms of ...

Clinical research led by Indiana University School of Medicine investigators and their collaborators in Uganda has revealed that hydroxyurea significantly reduces infections in children with sickle ...