A groundbreaking new book – the first of its kind in Chinese – is now available to empower researchers with the powerful tool of Mendelian randomization. Translated from the esteemed text "Mendelian ...

Researchers at Columbia University Mailman School of Public Health have developed a novel computational pipeline designed to identify protein biomarkers associated with complex diseases, including ...

Traditional epidemiological studies have identified numerous potential risk factors, but observational studies have struggled to establish causal links due to confounding factors and reverse causation ...

A new study identifying 56 non-clinical risk factors associated with sudden cardiac arrest (SCA), spanning lifestyle, physical measures, psychosocial factors, socioeconomic status, and the local ...

Using MR-SPI and AlphaFold3, scientists unravel the molecular underpinnings of Alzheimer’s disease, identifying key protein changes that could reshape future treatments. Study: Deciphering proteins in ...

A Mendelian randomization analysis supported an increasing causal relationship between asthma and lung cancer risk, particularly in smokers and lung squamous cell carcinoma. Individuals with asthma ...

Metabolic dysfunction-associated steatotic liver disease (MASLD) and sarcopenia frequently coexist, yet their causal relationship and underlying ...