Non-inferiority trials are a valuable type of clinical trial to evaluate new treatments that might have differing benefits. Such trials are increasingly used, but have methodological challenges in ...

The Galleri-Medicare study called REACH (Real-world Evidence to Advance Multi-Cancer Early Detection Health Equity) is a non-randomized, observational study of 50,000 Medicare beneficiaries. The ...

Antibiotic management of acute uncomplicated appendicitis among children was inferior to appendectomy, a randomized non-inferiority trial showed. For nearly 850 children with available primary outcome ...

Medical research is essential for advancing the understanding of health, diseases, and treatments. There are many types of studies that serve different purposes. Medical research, or health research, ...