Acute myeloid leukemia (AML) remains one of the most difficult blood cancers to treat. Although drug combinations are often more effective than single agents, their true mechanisms of action have been ...

A large share of medicines developed today may never reach patients for a surprisingly simple reason: they cannot dissolve well enough in water. For most treatments, the oral route remains the gold ...

These plots show powder X-ray diffraction measurements of three different types of formulations: simple mixing (a, d), the conventional evaporation/condensation ...

Poor drug solubility has become a challenge for pharmaceutical companies, with an approximation of 40% of drugs in their developing stages demonstrating problems with drug solubility. Additionally, ...