An AI model that screens ionizable lipids by 3D conformation identified a candidate 14.8 times more efficient than current ...
A new artificial intelligence model can improve the process of drug and vaccine discovery by predicting how efficiently specific mRNA sequences will produce proteins, both generally and in various ...
mRNA (red) is transported from the cell nucleus to the cytosol though a nuclear pore in complex with several proteins (white), including a helicase, Tap and Rae1, which interacts with the nucleoporin ...
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AI-guided LNP design for targeted in vivo mRNA delivery
Messenger RNA (mRNA) therapeutics have moved from a promising idea to clinical reality, accelerating vaccine development and ...
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Could COVID-19 mRNA vaccines also fight cancer?
The mass-produced COVID-19 vaccines built using the mRNA model – which were rapidly manufactured during the global pandemic – could also help the immune system recognise and attack cancer tumours, new ...
In two experiments, researchers have found that introducing people to "mental models" about how mRNA vaccination works and how the body protects itself from foreign DNA can preemptively or reactively ...
The Food and Drug Administration has reversed course and agreed to review Moderna’s application for the first mRNA-based flu vaccine under a revised approach, company and federal officials said ...
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